Contribution of acrB upregulation & OmpC/Ompk36 loss over the presence of blaNDM towards carbapenem resistance development among pathogenic Escherichia coli & Klebsiella spp.
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چکیده
منابع مشابه
Carbapenem resistance in a rural part of southern India: Escherichia coli versus Klebsiella spp.
Carbapenems are regularly used as the last choice for the management of multidrug-resistant E. coli and Klebsiella infections3. However, the recent emergence and dissemination of carbapenem resistance raise a question on the effectiveness of empirical therapy with carbapenems4,5. In India, there are no valid data on the prevalence of carbapenem-resistant Enterobacteriaceae (CRE)6; although a fe...
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abstract the present study tried to investigate the effect of visual aids (films) on the development of the speech act of disagreement among iranian efl intermediate learners. to this end, the researcher selected 40 homogeneous intermediate learners based on their scores on oxford placement test. .the subjects then divided into control group and experimental group. both classes were tested by ...
Evaluation of Efflux pump activity among Uropathogenic Escherichia coli and Klebsiella pneumonia multiple- Drug Resistance isolates
Antibiotic resistance is a phenomenon in which antibiotic used to treat bacteria becomes useless due to resistance mechanism. Increased drug resistance and occurrence of Multiple Drug Resistance in bacteria specificity nosocomial and Urinary Tract Infection bacteria has reduced the possibilities of treating these infectious diseases. Efflux pumps are one of the major mechanism of MDR in bacteri...
متن کاملEscherichia coli: development of carbapenem resistance during therapy.
A 76-year-old woman had recurrent urosepsis due to extended-spectrum beta -lactamase-positive Escherichia coli. Imipenem resistance was detected after long-term imipenem-meropenem therapy. The carbapenem-hydrolyzing enzyme gene was identified as blaKPC-3. To our knowledge, this is the first documented case in which carbapenem-resistant E. coli emerged during therapy with imipenem and meropenem,...
متن کاملKlebsiella pneumoniae: Development of Carbapenem Resistance due to Acquisition of blaNDM-1 During Antimicrobial Therapy in Twin Infants with Pneumonia
OBJECTIVES To identify the mechanism of in vivo development of carbapenem resistance in Klebsiella pneumoniae. METHODS Seven sequential isolates of K. pneumoniae were obtained from twin infants with pneumonia. Antimicrobial susceptibility testing was performed by agar dilution method. Carbapenemases including KPC and MβL were initially screened using phenotypic methods, and carbapenemase-enco...
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ژورنال
عنوان ژورنال: Indian Journal of Medical Research
سال: 2019
ISSN: 0971-5916
DOI: 10.4103/ijmr.ijmr_716_17